Size  100ug
Cat code  200329
Species Cross-reactivity  H
Key Application  WB,ICC
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG1
Molecular Weight  50kDa
Sensitivity  This antibody detects endogenous levels Keratin 7 and does not cross-react with related proteins.
Immunogen  Purified recombinant human Keratin 7 protein fragments expressed in E.coli.
UniProt Number  P08729
GeneBank ID  NM_005556
Subcellular location  Cytoplasm
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername  K7; CK7; SCL; K2C7; MGC3625; MGC129731
Gene_symbol  K7; CK7; SCL; K2C7
Summary  The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
UniPort summary  Function  Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Application Images :  
Western blot detection of Keratin 7(N-terminus) antibody in A459&Hela cell lysates using Keratin 7(N-terminus) antibody (1:1000 diluted).
Predicted band size: 50KDa
Observed band size: 50KDa.
Immunocytochemistry of HeLa cells using anti- Keratin 7(N-terminus) antibody diluted 1:150.