Size  100ul
Cat code  220020
Species Cross-reactivity  H
Key Application  WB
Host  Mouse
Clone Number  1H6-E9-E6
Antibody type  Monoclonal antibody
Purified method  
Isotype  IgG1
Molecular Weight  41kDa
Sensitivity  The antibody detects endogenous level of total KRT19 protein.
Immunogen  Purified recombinant fragment of human KRT19 expressed in E. Coli.
UniProt Number  P08727
GeneBank ID  NM_002276.4
Subcellular location  
Formulation  Ascitic fluid containing 0.03% sodium azide.
Altername  40 kDa keratin intermediate filament ; CK 19 ; CK-19 ; ck19 ; Cytokeratin 19 ; Cytokeratin-19 ; k19 ; K1C19_HUMAN ; k1cs ; Keratin 19 ; Keratin type I 40 kD ; Keratin type i 40kD ; Keratin type I cytoskeletal 19 ; Keratin, type I cytoskeletal 19 ; Keratin, type I, 40 kd ; Keratin-19 ; krt19 ; mgc15366 ;
Gene_symbol  K19; CK19; K1CS
Summary  The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
UniPort summary  Function  Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Application Images :  
Western blot detection of KRT19 antibody in CaCo2, HepG2 and T-47D cell lysates using KRT19 antibody(dilution 1:500).Predicted band size:41Kda.Observed band size:41KDa.