Size  100ul
Cat code  220015
Species Cross-reactivity  H
Key Application  WB
Host  Mouse
Clone Number  7A7-H3-D5
Antibody type  Monoclonal antibody
Purified method  
Isotype  IgG1
Molecular Weight  102kDa
Sensitivity  The antibody detects endogenous level of total HK1 protein.
Immunogen  Purified recombinant fragment of human HK1 expressed in E. Coli.
UniProt Number  P19367
GeneBank ID  NM_000188.2
Subcellular location  Mitochondrion outer membrane. Note: Its hydrophobic N-terminal sequence may be involved in membrane binding
Formulation  Ascitic fluid containing 0.03% sodium azide.
Altername  BB404130 ; Brain form hexokinase ; dea ; EC 2.7.1.1 ; Glycolytic enzyme ; HEXOKIN ; Hexokinase PI ; Hexokinase type I ; Hexokinase, tumor isozyme ; Hexokinase-1 ; Hexokinase-A ; HK I ; HK1 ; HK1 tb ; Hk1-s ; HK1-ta ; HK1-tb ; HK1-tc ; HKI ; HXK1 ; HXK1_HUMAN ; mHk1-s ;
Gene_symbol  HKD; HKI; HXK1; HMSNR; HK1-ta; HK1-tb; HK1-tc
Summary  Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. [provided by RefSeq, Apr 2009]
UniPort summary  Function  null
Application Images :  
Western blot detection of HK1 antibody in Jurkat, HepG2 and Hela cell lysates using HK1 antibody(dilution 1:500).Predicted band size:102KDa.Observed band size:102KDa.