Size  100ug
Cat code  200753
Species Cross-reactivity  H,M,R
Key Application  WB,IP
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG2b
Molecular Weight  69kDa
Sensitivity  This antibody detects endogenous levels of SWAP70 and does not cross-react with related proteins.
Immunogen  Purified recombinant human SWAP70 protein fragments expressed in E.coli.
UniProt Number  Q9UH65
GeneBank ID  NM_015055.2
Subcellular location  Cytoplasm. Cell membrane. Nucleus. Cell projection ? lamellipodium.
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
Altername  Switch-associated protein 70
Gene_symbol  HSPC321; SWAP-70; FLJ39540; KIAA0640
Summary  null
UniPort summary  Function  Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which,
independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane
ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated
phosphatidylinositol (3,4)-bisphosphate production and cell protrusion
Application Images :  
Western blot detection of SWAP70 in Rat liver，Daudi，3T3，Raw264.7，Hela&PC12 cell lysates and  using SWAP70 antibody (1:1000 diluted). 
Predicted band size: 70KDa 
Observed band size: 70KDa
Immunoprecipitation analysis of Hela cell lysate using SWAP70 antibody.