Size  100ug
Cat code  200654
Species Cross-reactivity  H,M
Key Application  WB
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG1
Molecular Weight  160kDa
Sensitivity  This antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins.
Immunogen  Purified recombinant human LRRFIP1 protein fragments expressed in E.coli.
UniProt Number  Q32MZ4
GeneBank ID  NM_004735.3
Subcellular location  Nucleus. Cytoplasm
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername  GC-binding factor 2
TAR RNA-interacting protein
Gene_symbol  GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1 
Summary  null
UniPort summary  Function  Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5´-AGCCCCCGGCG-3´) and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Application Images :  
Western blot detection of LRRFIP1 in Raji,C2C12,MCF7&Jurkat cell lysates using LRRFIP1 antibody (1:1000 diluted).
Predicted band size:89KDa.
Observed band size:160KDa