Size  100ug
Cat code  200569
Species Cross-reactivity  H,R
Key Application  WB,FC
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG1
Molecular Weight  102kDa
Sensitivity  This antibody detects endogenous levels Hexokinase-2( N-terminus) and does not cross-react with related proteins.
Immunogen  Purified recombinant human Hexokinase-2( N-terminus)  protein fragments expressed in E.coli.
UniProt Number  P52789
GeneBank ID  NM_000189
Subcellular location  Mitochondrion outer membrane
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername  HKII; HXK2
Gene_symbol  HKII; HXK2
Summary  Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]
UniPort summary  Function  null
Application Images :  
Western blot detection of Hexokinase-2(N-terminus) antibody in PC12,Hela&Jurkat lysates using Hexokinase-2(N-terminus) antibody (1:1000 diluted).
Predicted band size: 102KDa
Observed band size: 102KDa.
Flow Cytometry analysis of K562 cells stained with Hexokinase-2(N-terminus) (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.