Size  100ug
Cat code  200092
Species Cross-reactivity  H
Key Application  WB,IP,ICC
Host  Mouse
Antibody type  Monoclonal antibody
Purified method  Affinity purified
Isotype  IgG1
Molecular Weight  130kDa
Sensitivity  This antibody detects endogenous levels of KIF11 and does not cross-react with related proteins.
Immunogen  Purified recombinant human  KIF11 protein fragments expressed in E.coli.
UniProt Number  P52732
GeneBank ID  NM_004523
Subcellular location  Cytoplasm
Formulation  Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername  EG5;HKSP;KIF11;KIF11_HUMAN;kinesin family member 11;Kinesin like protein 1;Kinesin like spindle protein HKSP;Kinesin-like protein 1;Kinesin-like protein KIF11;Kinesin-like spindle protein HKSP;Kinesin-related motor protein Eg5;KNSL1;MCLMR;Thyroid receptor interacting protein 5;Thyroid receptor-interacting protein 5;TR-interacting protein 5;TRIP-5;TRIP5
Gene_symbol  EG5; HKSP; KNSL1; TRIP5 
Summary  This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.
UniPort summary  Function  Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays. 
Application Images :  
Western blot detection of KIF11 in MCF7,293T&Hela cell lysates using KIF11 antibody (1:1000 diluted).
Predicted band size:120KDa.
Observed band size:130KDa
Additional band size:75K
Immunocytochemistry stain of Hela using KIF11 antibody (1:200).
Immunoprecipitation analysis of Jurkat cell lysates using KIF11 antibody